Flavonoids with antiplasmodial and cytotoxic activities of Macaranga triloba
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چکیده
منابع مشابه
Cytotoxic prenylated bibenzyls and flavonoids from Macaranga kurzii.
One unique prenylated bibenzyl, kurzphenol A (1), two new prenylated flavonoids, kurzphenols B and C (2 and 3), as well as fourteen known compounds (4-17) were isolated from the twigs of Macaranga kurzii. Compound 1 was the first example of prenylated bibenzyl which possesses a benzofuran ring. All the known compounds were isolated from M. kurzii for the first time. Their structures were elucid...
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Macaranga triloba belongs to the family of Euphorbiaceae. Investigation on the dichloromethane extract of flower of Macaranga triloba collected at Hulu Terengganu, Malaysia has yielded four flavanone compounds known as 6-prenyl-3’-methoxy-eriodictyol (1), nymphaeol-B (2), nymphaeol-C (3) and 6-farnesyl3’,4’,5,7-tetrahydroxyflavanone (4). The structures of these compounds were elucidated based o...
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Background: Malaria continues to cause heavy morbidity and mortality and it is the fifth leading cause of death globally. The disease causes over one million deaths annually and affects many more, particularly due to increasing multi-drug resistant strains of Plasmodium falciparum. Sustained investigations in both curative and prophylactic interventions have supported the ethno-pharmacological ...
متن کاملFlavonoids and isoflavonoids with antiplasmodial activities from the root bark of Erythrina abyssinica.
From the root bark of Erythrina abyssinica a new pterocarpene [3-hydroxy-9-methoxy-10-(3,3-dimethylallyl)pterocarpene] and a new isoflav-3-ene [7,4'-dihydroxy-2',5'-dimethoxyisoflav-3-ene] were isolated. In addition, the known compounds erycristagallin, licoagrochalcone A, octacosyl ferulate and triacontyl 4-hydroxycinnamate were identified. The structures were determined on the basis of spectr...
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ژورنال
عنوان ژورنال: Fitoterapia
سال: 2012
ISSN: 0367-326X
DOI: 10.1016/j.fitote.2012.04.020